LeucoTox integrates cutting-edge molecular biology with the ground-breaking developments in immuno-oncology that have occurred in oncology over the last years. This enables LeucoTox to generate state-of-the-art models to test unprecedented therapeutic approaches to leukemia therapy. The team at LeucoTox has dissected the signaling pathways controlling cellular integrity in leukemia over several years to understand vulnerabilities inherent to leukemic cells and devise strategies to utilize these vulnerabilities for drug development purposes.